Southern Squash Casserole

Name: Southern Squash Casserole
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 6 servings
Ingredients: 4 cups sliced yellow squash; 1 cup chopped onion; 1 cup shredded cheddar cheese; 1 cup crushed saltine crackers; 1/2 cup milk; 2 eggs; 1/4 cup butter, melted; 1 teaspoon salt; 1/2 teaspoon black pepper; 1 teaspoon garlic powder

Highlighted under: Comfort Food

Savor the comforting taste of Southern Squash Casserole, a delightful blend of fresh squash, creamy cheese, and savory spices. This easy-to-make dish is perfect as a side for your family gatherings or a cozy weeknight meal, bringing a touch of Southern hospitality to your table. With its rich flavors and satisfying texture, it’s sure to become a staple in your recipe collection.

Created by

Lacey Montgomery

Last updated on 2025-12-13T17:42:12.885Z

This Southern Squash Casserole recipe has been passed down through generations, embodying the heartwarming essence of family meals around the table.

        Why You'll Love It
        Quick and easy to prepare.
Perfect for gatherings and weeknight dinners.
Deliciously creamy with a cheesy finish.

      

A Perfect Side Dish

Southern Squash Casserole stands out as an ideal side dish for any occasion. Its combination of textures—from tender squash to crunchy cracker topping—creates a harmonious balance on your plate. Whether you’re serving it with fried chicken, grilled meats, or a hearty stew, this casserole complements a wide variety of main dishes. The pleasing presentation and rich flavors make it a wonderful addition to family gatherings or potlucks, where it is sure to impress your loved ones.

This comforting casserole can easily transition from a holiday dinner to a casual weeknight meal. Its versatility ensures you can serve it year-round, adapting to the seasons and your family's tastes. Plus, its simplicity in preparation means you can enjoy more quality time with your family and less time in the kitchen.

Health Benefits of Squash

Yellow squash, the star ingredient in this casserole, is not only delicious but also packed with nutrients. It’s low in calories and high in vitamins, particularly Vitamin C, which is essential for a healthy immune system. Furthermore, squash is rich in antioxidants that help combat oxidative stress, making it a fantastic choice for those looking to incorporate more nutritious options into their meals.

Adding this casserole to your diet can be an excellent way to increase your vegetable intake. When combined with dairy products like cheddar cheese and the wholesome goodness of eggs, you'll create a dish that's not only satisfying but also nutritionally balanced, providing your body with essential nutrients for everyday vitality.

Casserole Variations

While this Southern Squash Casserole recipe is already a crowd-pleaser, there are numerous ways to customize it. Consider adding other vegetables such as zucchini, bell peppers, or even spinach for added color and nutrition. For a spicy kick, a dash of cayenne pepper or chopped jalapeños can elevate the flavors, making it a party on your palate.

If you're seeking to reduce calories or dairy, alternative ingredients can be used without sacrificing flavor. Substitute the cheddar cheese for a dairy-free option or use whole grain crackers for added fiber. These simple modifications can cater to various dietary preferences while preserving the comforting essence of this Southern classic.

Ingredients

Main Ingredients

4 cups sliced yellow squash
1 cup chopped onion
1 cup shredded cheddar cheese
1 cup crushed saltine crackers
1/2 cup milk
2 eggs
1/4 cup butter, melted
1 teaspoon salt
1/2 teaspoon black pepper
1 teaspoon garlic powder

Gather all ingredients before starting to ensure a smooth cooking process.

Instructions

Prepare the Squash

Preheat your oven to 350°F (175°C). In a large pot, bring water to a boil and add the sliced squash and chopped onion. Cook for about 5 minutes until tender. Drain and set aside.

Mix the Ingredients

In a large mixing bowl, combine the cooked squash and onion with cheddar cheese, crushed saltine crackers, milk, eggs, melted butter, salt, pepper, and garlic powder. Stir until well blended.

Bake the Casserole

Transfer the mixture to a greased 9x13-inch baking dish. Spread evenly and bake for 30-35 minutes, or until the top is golden and bubbly.

Let the casserole cool for a few minutes before serving.

Tips for Perfecting Your Casserole

For the best results, ensure that you properly drain the cooked squash and onions before mixing them with the other ingredients. Excess moisture could lead to a soggy casserole, detracting from its overall texture. A simple way to achieve this is to place the drained vegetables in a clean towel and gently press out any additional liquid.

Another tip is to let the casserole rest for a few minutes after baking. This allows it to set up slightly, making it easier to serve. Not only does this enhance the flavor as the ingredients meld together, but it also creates a more appealing presentation for your guests.

Storing and Reheating Leftovers

If you find yourself with leftovers, Southern Squash Casserole stores well in the refrigerator for up to three days. To keep it fresh, transfer any unused casserole to an airtight container. When you’re ready to enjoy it again, simply reheat individual portions in the microwave or place the entire dish back in the oven until thoroughly warmed through.

For longer storage, consider freezing the casserole. Cover it tightly with aluminum foil or plastic wrap, and it can last for several months in the freezer. When you're ready to enjoy a comforting taste of Southern hospitality, just thaw in the refrigerator overnight and reheat when you're ready to serve.

Questions About Recipes

→ Can I make this casserole ahead of time?

Yes, you can prepare the mixture a day in advance and bake it just before serving.

→ What can I serve with Southern Squash Casserole?

This dish pairs wonderfully with grilled chicken, fish, or a fresh salad.